
What is coenzyme Q10? Why Q10? What role does this compound play in human life? Is it relevant whether a complex with it strengthens human immunity?
Scientifically, all coenzymes are called benzoquinone coenzymes. They contain a quinoid group (hence the Q symbol) and several isoprenyl groups (with the following index: 6, 8, 9, 10).
Coenzyme Q10 is coenzyme Q10 or ubiquinone. This substance is found in almost all cells of the body, in the mitochondria.
In humans, unlike animals, ubiquinone is only present with 10 isoprene units, hence the importance of Q10.
The substance is synthesized in the body from mevalonic acid and derivatives of tyrosine and phenylalanine, but the amount is not always sufficient.
The coenzyme is essential for the normal functioning of living organisms and is particularly important for the functioning of tissues with high energy metabolism.
The highest concentration of coenzyme Q10 is found in heart muscle tissue.
This substance protects against the action of free radicals and thus contributes to strengthening immunity.
High blood pressure
Several clinical trials involving small numbers of people suggest that CoQ10 may lower blood pressure. It may take 4 to 12 weeks to see any change. In one analysis that reviewed 12 clinical trials, researchers concluded that CoQ10 may lower systolic blood pressure by up to 17 mm Hg and diastolic blood pressure by 10 mm Hg, without significant side effects. More studies with larger numbers of people are needed. Do not try to treat high blood pressure yourself. Talk to your doctor about treatment.
Diabetes
CoQ10 supplements may improve heart health and blood sugar levels and help manage high blood pressure in people with diabetes. Preliminary studies have found that CoQ10 improves blood sugar levels. But other studies have not shown any effect. If you have diabetes, talk to your doctor or registered dietitian before taking CoQ10.
High cholesterol
People with high cholesterol tend to have lower levels of CoQ10, so CoQ10 has been suggested as a treatment for high cholesterol, but research is lacking. There is evidence that it can reduce the side effects of common cholesterol-lowering drugs called statins, which reduce the body's natural levels of CoQ10. Taking CoQ10 supplements can help bring levels back to normal. Research also suggests that CoQ10 may help reduce muscle pain associated with statin therapy. Ask your doctor if taking CoQ10 with a statin is right for you.
Gum disease (periodontitis)
Gum disease is a common problem that causes swollen, bleeding, painful, and red gums. Clinical studies show that people with gum disease have low levels of CoQ10 in their gums. Several studies involving small numbers of people have found that CoQ10 supplements have helped speed up healing and tissue repair, but more research is needed.
Other
Preliminary clinical studies also suggest that CoQ10 may:
- Improve immune function in people with HIV or AIDS
- Increase sperm motility, improving male fertility
- To be used as part of the treatment for Parkinson's disease
- Improve the condition of people with angina pectoris
- Help prevent migraines
More research is needed to determine whether CoQ10 can be used safely and effectively to address these health concerns and needs.
With age, the production of necessary substances decreases, which leads to a decrease in the concentration of coenzyme Q and its deficiency. Already at the age of 40, its content in cells decreases by 30%, - at 60 - we already lack half of the important substance. If a person has concomitant diseases, the synthesis of the substance can decrease even more.
Where to get coenzyme Q10? It is found in foods such as red palm oil, beef, liver, oily fish, herring, roasted peanuts, sesame, and pistachios. There are also many supplement complexes that contain coenzyme Q10.