Dimethylglycine (DMG) is an amino acid found naturally in plant and animal cells and in many foods, such as beans, grains, brown rice, pumpkin seeds, and animal liver. It is used to improve energy, boost the immune system, and relieve seizures and symptoms of autism spectrum disorder.
DMG is an important methyl donor involved in many biochemical processes and important for
glutathione synthesis.
DMG is the abbreviation for dimethylglycine, an amino acid with the chemical formula (CH3)2NCH2COOH. It is derived from glycine, which is one of the 20 amino acids most commonly used in the synthesis of proteins in humans. When DMG was first discovered, it was initially named vitamin B16. However, it was later discovered that DMG is synthesized in the body, which means that it is not classified as a vitamin.
DMG is produced by many biochemical processes in the human body, such as the citric acid cycle, also known as the Krebs cycle. It is also a byproduct
of choline metabolism. DMG is formed in small amounts during these processes because it is rapidly broken down. The most important dietary sources of DMG are protein-rich foods, such as beans and organ meats, especially liver. It is also formed by the removal of a methyl group from trimethylglycine, which is found in many plants.
In dietary supplements, DMG is often found in the form of its hydrochloride salt, commonly referred to as DMG HCL. The synthesis of this form of DMG involves the alkylation of glycine using formic acid and formaldehyde. This product is then converted to DMG HCL by the addition of hydrochloric acid. DMG HCL can be converted to free form DMG by neutralizing it with an oxide, usually silver oxide.
Supporting the immune system is one of the most common uses for DMG HCL supplements. It can also help support energy levels, weight management, and healthy behaviors.
Signs that you may need DMG HCL
A compromised immune system is one of the most important signs that you may need DMG HCL supplements. A weak immune system often leads to chronic illnesses or injuries that never heal. Low stamina may also mean that you may benefit from DMG supplements. Additional signs that may indicate that you may need DMG include the need to maintain a healthy weight. Children with erratic behavior may also benefit from DMG.